Description

1-(5-Fluoro-2-Nitrophenyl)Propan-2-One is a high-purity fluorinated aromatic ketone building block, identified by CAS NO 1266659-06-6. This compound is valued for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), especially those containing fluorinated and nitro-substituted aromatic systems.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Organic Synthesis Building Block: Serves as a versatile precursor for further chemical transformations, including reduction, cyclization, and functional group interconversion reactions.
• Material Science: Potential intermediate in the synthesis of specialty polymers, liquid crystals, or organic electronic materials due to its conjugated nitro and ketone functionalities.
• Chemical Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	1-(5-Fluoro-2-Nitrophenyl)Propan-2-One
CAS No.	1266659-06-6
Molecular Formula	C9H8FNO3
Molecular Weight	197.16 g/mol
Synonyms	1-(5-Fluoro-2-nitrophenyl)propan-2-one; 2-Propanone, 1-(5-fluoro-2-nitrophenyl)-; 5-Fluoro-2-nitropropiophenone; 2-Nitro-5-fluoropropiophenone; 1-Propan-2-yl-5-fluoro-2-nitrobenzene; 2-Acetyl-4-fluoronitrobenzene; 4-Fluoro-2-nitropropiophenone; 1-(5-Fluoro-2-nitrophenyl)acetone
EINECS	Contact for details

Quality Control

Our 1-(5-Fluoro-2-Nitrophenyl)Propan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.