Description

1-Fluoro-4-Nitro-2-(2,2,2-Trifluoroethyl)-Benzene is a high-value, multi-fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both aromatic fluorine and a trifluoroethyl side chain, makes it a critical intermediate for developing novel compounds with tailored properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to incorporate fluorinated motifs to modulate bioactivity, metabolic stability, and lipophilicity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in creating fluorinated drug candidates for oncology, CNS disorders, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a building block for synthesizing specialty polymers, liquid crystals, and organic electronic materials that benefit from fluorinated aromatic units.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reactions, such as nucleophilic aromatic substitution (SNAr), and for creating complex molecular libraries.
• Fluorine Chemistry Studies: An important compound for investigating structure-activity relationships (SAR) and the effects of polyfluorination on molecular properties.

Basic Information

Product Name	1-Fluoro-4-Nitro-2-(2,2,2-Trifluoroethyl)-Benzene
CAS No.	1262413-56-8
Molecular Formula	C8H5F4NO2
Molecular Weight	223.13 g/mol
Synonyms	2-(2,2,2-Trifluoroethyl)-1-fluoro-4-nitrobenzene; 4-Nitro-2-(2,2,2-trifluoroethyl)fluorobenzene; 1-Fluoro-4-nitro-2-(trifluoroethyl)benzene; α,α,α-Trifluoro-2-fluoro-5-nitroethylbenzene; Benzene, 1-fluoro-4-nitro-2-(2,2,2-trifluoroethyl)-; 5-Nitro-2-(2,2,2-trifluoroethyl)fluorobenzene
EINECS	Contact for details

Quality Control

Our production of 1-Fluoro-4-Nitro-2-(2,2,2-Trifluoroethyl)-Benzene adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to verify identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.