Description

2-Fluoro-4-Nitro-1-(2,2,2-Trifluoroethyl)Benzene is a high-value fluorinated aromatic building block, distinguished by its unique combination of fluorine, nitro, and trifluoroethyl substituents. This compound is critical for enabling precise molecular modifications in advanced synthetic chemistry, offering superior reactivity and stability for demanding applications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals with tailored electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex fluorinated motifs.
• Chemical Biology Probe Development: Utilized for labeling and modifying biomolecules to study protein-ligand interactions and cellular processes.

Basic Information

Product Name	2-Fluoro-4-Nitro-1-(2,2,2-Trifluoroethyl)Benzene
CAS No.	1262412-94-1
Molecular Formula	C8H5F4NO2
Molecular Weight	223.13 g/mol
Synonyms	1-(2,2,2-Trifluoroethyl)-2-fluoro-4-nitrobenzene; 2-Fluoro-4-nitro(2,2,2-trifluoroethyl)benzene; 2-Fluoro-4-nitro-α,α,α-trifluoroethylbenzene; 4-Nitro-2-fluoro-1-(2,2,2-trifluoroethyl)benzene; Benzene, 2-fluoro-4-nitro-1-(2,2,2-trifluoroethyl)-; 1262412-94-1; α,α,α-Trifluoro-2-fluoro-4-nitrotoluene
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Nitro-1-(2,2,2-Trifluoroethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.