Description

2-Fluoro-3-Formyl-Benzonitrile is a versatile and high-value aromatic building block featuring both a formyl and a nitrile functional group on a fluorinated benzene ring. This unique bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers due to its electron-withdrawing groups.
• Chemical Biology Probes: Utilized as a scaffold for designing fluorescent probes and molecular tags for bioimaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-3-Formyl-Benzonitrile
CAS No.	1261823-31-7
Molecular Formula	C8H4FNO
Molecular Weight	149.12 g/mol
Synonyms	3-Cyano-2-fluorobenzaldehyde; 2-Fluoro-3-cyanobenzaldehyde; 3-Formyl-2-fluorobenzonitrile; 2-Fluoroisophthalonitrile aldehyde; Benzaldehyde, 3-cyano-2-fluoro-; 2-Fluoro-3-formylbenzonitrile; 1261823-31-7
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Formyl-Benzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.