Description

2-Bromo-4-(Difluoromethoxy)Benzonitrile is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is valued for its unique molecular structure, which incorporates bromine, difluoromethoxy, and nitrile functional groups, enabling precise chemical modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, particularly in medicinal chemistry programs targeting new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates in early-stage drug discovery and development.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides and fungicides.
• Material Science Research: Serves as a precursor for the development of specialty polymers and liquid crystals due to its aromatic and halogenated structure.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex aromatic motifs.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-Bromo-4-(Difluoromethoxy)Benzonitrile
CAS No.	1261818-72-7
Molecular Formula	C8H4BrF2NO
Molecular Weight	248.03 g/mol
Synonyms	4-(Difluoromethoxy)-2-bromobenzonitrile; 2-Bromo-4-(difluoromethoxy)benzonitrile; Benzonitrile, 2-bromo-4-(difluoromethoxy)-; 1261818-72-7; 2-Bromo-4-difluoromethoxy-benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(Difluoromethoxy)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.