Description

2,4-Difluoro-6-Hydroxybenzonitrile is a high-purity fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its unique molecular scaffold, featuring both a nitrile and a hydroxyl group on a difluorinated benzene ring, makes it a versatile precursor for constructing complex molecules. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Serves as a critical building block in the development of next-generation herbicides, fungicides, and pesticides, leveraging the bioactivity-enhancing properties of fluorine atoms.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic materials, where its fluorinated aromatic structure contributes to desired electronic properties and stability.
• Functional Polymer Monomer: Acts as a specialty monomer for creating high-performance polymers with specific chemical resistance, thermal stability, or surface properties.
• Chemical Synthesis Reagent: Employed in organic synthesis as a versatile precursor for further functionalization, including hydrolysis, reduction, and cyclization reactions to create heterocyclic compounds.

Basic Information

Item	Details
Product Name	2,4-Difluoro-6-Hydroxybenzonitrile
CAS No.	1261793-35-4
Molecular Formula	C7H3F2NO
Molecular Weight	155.10 g/mol
Synonyms	6-Cyano-2,4-difluorophenol; 2,4-Difluoro-6-hydroxybenzenecarbonitrile; 2,4-Difluorophenol-6-carbonitrile; 2,4-Difluoro-6-phenol carbonitrile; 6-Hydroxy-2,4-difluorobenzonitrile; 2,4-Difluoro-6-hydroxyl benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-6-Hydroxybenzonitrile is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.