Description

3,6-Difluoro-2-Methoxyphenylacetonitrile is a versatile fluorinated aromatic nitrile building block, essential for the synthesis of complex organic molecules. Its value lies in the strategic placement of fluorine and methoxy substituents, which are critical for modulating the electronic properties, lipophilicity, and metabolic stability of target compounds. This high-purity intermediate is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-infective research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in advanced display technologies.
• Organic Electronic Materials: Employed in the research and production of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) for constructing complex biaryl systems.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and creating specialized chemical libraries for screening.

Basic Information

Product Name	3,6-Difluoro-2-Methoxyphenylacetonitrile
CAS No.	1261760-73-9
Molecular Formula	C9H7F2NO
Molecular Weight	183.15 g/mol
Synonyms	2-(3,6-Difluoro-2-methoxyphenyl)acetonitrile; (3,6-Difluoro-2-methoxyphenyl)acetonitrile; 3,6-Difluoro-2-methoxybenzyl cyanide; 1261760-73-9; α-Cyano-3,6-difluoro-2-methoxytoluene; 2-Methoxy-3,6-difluorophenylacetonitrile
EINECS	Contact for details

Quality Control

Our 3,6-Difluoro-2-Methoxyphenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.