Description

4-Bromo-2-(Difluoromethyl)Benzonitrile is a high-value, multi-functional aromatic intermediate featuring both bromine and difluoromethyl substituents on a benzonitrile core. This unique structure makes it a critical building block for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its halogen and fluorine atoms are leveraged for tuning electronic properties and metabolic stability. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides, where the difluoromethyl group can enhance lipophilicity and bioactivity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing aromatic compounds used in electronic display technologies.
• Organic Synthesis Building Block: The bromine atom allows for further functionalization via cross-coupling reactions (e.g., Suzuki, Negishi), enabling rapid diversification of chemical libraries.
• Fluorine Chemistry Research: An important compound for studying the effects of difluoromethyl substitution on aromatic systems in medicinal and materials chemistry.

Basic Information

Product Name	4-Bromo-2-(Difluoromethyl)Benzonitrile
CAS No.	1261760-22-8
Molecular Formula	C8H4BrF2N
Molecular Weight	232.03 g/mol
Synonyms	2-(Difluoromethyl)-4-bromobenzonitrile; 4-Bromo-2-(difluoromethyl)benzonitrile; Benzonitrile, 4-bromo-2-(difluoromethyl)-; 1261760-22-8
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Difluoromethyl)Benzonitrile is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.