Description

2-(Bromomethyl)-6-Fluorobenzonitrile is a versatile and high-purity fluorinated aromatic building block. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its bromomethyl and nitrile groups offer valuable handles for further functionalization. It is primarily sought after by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and liquid crystals where the fluorine and nitrile groups modify material properties.
• Chemical Biology Probes: Useful for creating fluorescent tags or affinity probes due to its reactive bromomethyl group for bioconjugation.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluorinated aromatic architectures.

Basic Information

Product Name	2-(Bromomethyl)-6-Fluorobenzonitrile
CAS No.	1261686-95-6
Molecular Formula	C8H5BrFN
Molecular Weight	214.04 g/mol
Synonyms	6-Fluoro-2-(bromomethyl)benzonitrile; 2-Bromomethyl-6-fluorobenzonitrile; (6-Fluoro-2-cyanophenyl)methyl bromide; 2-Fluoro-6-(bromomethyl)benzonitrile; α-Bromo-6-fluoro-o-tolunitrile; 2-Cyano-3-fluorobenzyl bromide
EINECS	Contact for details

Quality Control

Every batch of 2-(Bromomethyl)-6-Fluorobenzonitrile is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.