Description

3-(Chloromethyl)-2-Fluorobenzonitrile is a versatile fluorinated aromatic nitrile building block, distinguished by its reactive chloromethyl and cyano functional groups. This compound is critical for the synthesis of complex molecules, offering chemists precise control over molecular architecture in advanced chemical processes. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates containing fluorinated aromatic systems.
• Agrochemical Synthesis: Serves as a crucial building block for creating advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for catalysis and molecular recognition studies in both academic and industrial chemistry.
• Material Science Research: Employed in the synthesis of monomers or functional units for advanced polymers and functional materials with tailored properties.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	3-(Chloromethyl)-2-Fluorobenzonitrile
CAS No.	1261682-61-4
Molecular Formula	C8H5ClFN
Molecular Weight	169.58 g/mol
Synonyms	2-Fluoro-3-(chloromethyl)benzonitrile; 3-(Chloromethyl)-2-fluorobenzonitrile; 2-Fluoro-3-chloromethylbenzonitrile; Benzonitrile, 3-(chloromethyl)-2-fluoro-; 1261682-61-4
EINECS	Contact for details

Quality Control

Our 3-(Chloromethyl)-2-Fluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The compound may be moisture-sensitive; handle and store under inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.