Description

2-Chloro-6-(Difluoromethoxy)Benzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzonitrile core with chloro and difluoromethoxy substituents. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modulation. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing next-generation compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Serves as a precursor for developing new herbicides and pesticides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the development of specialty chemicals and advanced materials, including liquid crystals and polymers.
• Organic Synthesis: Employed in cross-coupling reactions and as a versatile substrate for introducing the difluoromethoxy group into complex molecules.
• Contract Research & Manufacturing (CRAM): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	2-Chloro-6-(Difluoromethoxy)Benzonitrile
CAS No.	1261618-35-2
Molecular Formula	C8H4ClF2NO
Molecular Weight	203.57 g/mol
Synonyms	2-Chloro-6-(difluoromethoxy)benzonitrile; 6-Chloro-2-(difluoromethoxy)benzonitrile; Benzonitrile, 2-chloro-6-(difluoromethoxy)-; 1261618-35-2; 2-(Difluoromethoxy)-6-chlorobenzonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(Difluoromethoxy)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.