Description

2-Amino-3-Trifluoromethoxy-Benzonitrile is a high-value, multi-functional aromatic nitrile building block featuring both amino and trifluoromethoxy substituents. This compound is essential for medicinal chemistry and advanced materials research, offering a unique combination of electronic and steric properties that facilitate the development of novel active compounds. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of complex molecules, including potential agrochemicals and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Functional Material Precursor: Employed in the synthesis of organic electronic materials, dyes, and pigments.
• Chemical Biology Probe: Utilized in the design of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis Building Block: Provides a versatile starting point for contract research organizations (CROs) and custom synthesis houses.

Basic Information

Product Name	2-Amino-3-Trifluoromethoxy-Benzonitrile
CAS No.	1261581-55-8
Molecular Formula	C8H5F3N2O
Molecular Weight	202.14 g/mol
Synonyms	2-Amino-3-(trifluoromethoxy)benzonitrile; 3-Trifluoromethoxy-2-aminobenzonitrile; 2-Cyano-6-(trifluoromethoxy)aniline; Benzonitrile, 2-amino-3-(trifluoromethoxy)-; 2-Amino-alpha,alpha,α-trifluoro-m-anisonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Trifluoromethoxy-Benzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.