Description

3-Bromo-5-Nitro-1-(Difluoromethoxy)Benzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. Its unique structure, featuring bromo, nitro, and difluoromethoxy substituents, makes it a critical intermediate for introducing specific functionalities into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of compounds with fluorinated motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of its nitro and halogenated groups.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution in medicinal and process chemistry.
• Fluorine Chemistry: The difluoromethoxy group makes it a valuable synthon for introducing fluorine atoms into complex molecules to modulate their physicochemical properties.

Basic Information

Product Name	3-Bromo-5-Nitro-1-(Difluoromethoxy)Benzene
CAS No.	1261441-47-7
Molecular Formula	C7H4BrF2NO3
Molecular Weight	267.02 g/mol
Synonyms	1-Bromo-3-(difluoromethoxy)-5-nitrobenzene; 3-Bromo-5-nitro(difluoromethoxy)benzene; Benzene, 1-bromo-3-(difluoromethoxy)-5-nitro-; 5-Bromo-1-(difluoromethoxy)-3-nitrobenzene; 3-Bromo-5-nitro-α,α-difluoroanisole
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Nitro-1-(Difluoromethoxy)Benzene is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.