Description

3-Cyano-4-Fluorobenzyl Chloride is a versatile and high-value fluorinated aromatic building block essential for advanced organic synthesis. Its molecular structure, featuring both a reactive benzyl chloride group and a cyano substituent adjacent to a fluorine atom, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated cyanobenzyl groups into polymer chains, altering material properties like solubility and thermal stability.
• Cross-Coupling Reactions: The benzyl chloride moiety allows for efficient participation in palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Custom Synthesis & Contract Research: A valuable starting material for custom synthesis houses and CROs (Contract Research Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Cyano-4-Fluorobenzyl Chloride
CAS No.	1260892-59-8
Molecular Formula	C8H5ClFN
Molecular Weight	169.58 g/mol
Synonyms	4-Fluoro-3-cyanobenzyl chloride; (4-Fluoro-3-cyanophenyl)methyl chloride; 1-(Chloromethyl)-4-fluoro-2-cyanobenzene; 2-Cyano-4-fluorobenzyl chloride; α-Chloro-4-fluoro-3-cyanotoluene; 4-Fluoro-3-cyanobenzylchloride; 3-Cyano-4-fluorobenzylchloride
EINECS	Contact for details

Quality Control

Our production of 3-Cyano-4-Fluorobenzyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.