Description

5-Bromo-2,4-Difluorobenzonitrile is a high-purity, multi-functional aromatic building block characterized by its bromine, fluorine, and nitrile substituents. This compound is essential for facilitating complex molecular transformations in advanced chemical synthesis, offering precise reactivity for constructing sophisticated target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the difluoro and bromo groups impart desirable biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for liquid crystals, organic semiconductors, and advanced polymers, leveraging its rigid aromatic core and functional handles.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization campaigns to introduce specific halogenated motifs into drug candidates.
• Chemical Research: A versatile reagent for academic and industrial R&D in organic synthesis, enabling the exploration of new reaction methodologies and heterocyclic systems.

Basic Information

Product Name	5-Bromo-2,4-Difluorobenzonitrile
CAS No.	1260879-25-1
Molecular Formula	C7H2BrF2N
Molecular Weight	218.00 g/mol
Synonyms	2,4-Difluoro-5-bromobenzonitrile; 5-Bromo-2,4-difluorobenzene carbonitrile; Benzonitrile, 5-bromo-2,4-difluoro-; 1260879-25-1; 5-Br-2,4-F2-Ph-CN
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,4-Difluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.