Description

4-(Difluoromethoxy)-2,6-Difluorobenzonitrile is a specialized fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring a difluoromethoxy ether linkage and multiple fluorine atoms, makes it a valuable precursor for creating complex molecules with tailored electronic and steric properties. This high-purity intermediate is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorine atoms to modulate metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance biological activity and environmental profile.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronics: Employed in the synthesis of fluorinated organic semiconductors and charge-transport materials for OLEDs and other electronic devices.
• Advanced Polymer Chemistry: Acts as a monomer or modifier for introducing fluorine into high-performance polymers, improving chemical resistance and thermal stability.
• Chemical Research & Development: A versatile reagent for methodological studies in fluorination chemistry and the construction of complex heterocycles.

Basic Information

Product Name	4-(Difluoromethoxy)-2,6-Difluorobenzonitrile
CAS No.	1260862-43-8
Molecular Formula	C8H3F4NO
Molecular Weight	205.11 g/mol
Synonyms	2,6-Difluoro-4-(difluoromethoxy)benzonitrile; 4-(Difluoromethoxy)-2,6-difluorobenzonitrile; Benzonitrile, 4-(difluoromethoxy)-2,6-difluoro-; 2,6-Difluoro-4-(difluoromethoxy)benzonitrile
EINECS	Contact for details

Quality Control

Our production of 4-(Difluoromethoxy)-2,6-Difluorobenzonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.