Description

3-Fluoro-2-(Hydroxymethyl)Benzonitrile is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a reactive hydroxymethyl group and a nitrile moiety adjacent to a fluorine atom, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis and molecular recognition studies due to its functional group diversity.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Fluorine Chemistry Building Block: Essential for introducing the 2-fluoro-6-substituted benzyl motif into more complex molecular architectures.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects.

Basic Information

Item	Details
Product Name	3-Fluoro-2-(Hydroxymethyl)Benzonitrile
CAS No.	1260764-63-3
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	2-(Hydroxymethyl)-3-fluorobenzonitrile; 3-Fluoro-2-(hydroxymethyl)benzonitrile; 3-Fluoro-2-hydroxymethylbenzonitrile; (3-Fluoro-2-cyanophenyl)methanol; 2-Cyano-6-fluorobenzyl alcohol; Benzonitrile, 3-fluoro-2-(hydroxymethyl)-; 1260764-63-3
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-2-(Hydroxymethyl)Benzonitrile is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.