Description

3-Bromo-2-Fluoro-5-Methylbenzonitrile is a high-purity, multi-functional halogenated aromatic nitrile building block. This compound is essential for advanced organic synthesis, offering a unique combination of reactive sites for selective functionalization. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogen and nitrile functionalities.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and liquid crystals with tailored electronic properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Bromo-2-Fluoro-5-Methylbenzonitrile
CAS No.	1260741-40-9
Molecular Formula	C8H5BrFN
Molecular Weight	214.04 g/mol
Synonyms	2-Fluoro-3-bromo-5-methylbenzonitrile; 5-Methyl-3-bromo-2-fluorobenzonitrile; Benzonitrile, 3-bromo-2-fluoro-5-methyl-; 3-Bromo-2-fluoro-5-methyl-benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Fluoro-5-Methylbenzonitrile is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency, supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.