Description

[5-(Trifluoromethyl)-1,2,4-Oxadiazol-3-Yl]Methanol is a high-value fluorinated heterocyclic building block, specifically a functionalized 1,2,4-oxadiazole derivative. This compound matters for its unique trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability, lipophilicity, and bioavailability to final molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

This specialized chemical intermediate serves as a key scaffold in advanced organic synthesis, enabling the development of new compounds with improved performance characteristics.

• Pharmaceutical Intermediate: A crucial building block for synthesizing potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Employed in the research of advanced materials, such as liquid crystals or polymers, where fluorinated heterocycles can modify physical properties.
• Chemical Biology Probe Synthesis: Serves as a starting material for creating labeled compounds or probes used to study biological pathways and mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	[5-(Trifluoromethyl)-1,2,4-Oxadiazol-3-Yl]Methanol
CAS No.	1260674-38-1
Molecular Formula	C4H3F3N2O2
Molecular Weight	168.07 g/mol
Synonyms	3-(Hydroxymethyl)-5-(trifluoromethyl)-1,2,4-oxadiazole; (5-Trifluoromethyl-[1,2,4]oxadiazol-3-yl)-methanol; 5-(Trifluoromethyl)-3-oxadiazolemethanol; 3-Hydroxymethyl-5-trifluoromethyl-1,2,4-oxadiazole; (5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl)methanol; FTOH Oxadiazole derivative
EINECS	Contact for details

Quality Control

Our production of [5-(Trifluoromethyl)-1,2,4-Oxadiazol-3-Yl]Methanol adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.