Description

1-(Bromomethyl)-2,5-Difluoro-4-Nitrobenzene is a high-value, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is engineered to serve as a critical intermediate in the development of complex molecules, offering precise reactivity for selective functionalization. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and material science industries seeking to incorporate difluorinated and nitro-substituted motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing difluorobenzene and nitroarene pharmacophores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the bromomethyl and nitro groups enable further derivatization.
• Liquid Crystal & OLED Material Development: Serves as a building block for creating fluorinated aromatic cores essential in electronic and photonic materials.
• Cross-Coupling Reactions: The bromomethyl moiety makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex biaryl systems.
• Functional Polymer Monomer: Can be incorporated into polymer backbones to impart specific properties like altered solubility, thermal stability, or electronic characteristics.
• Organic Synthesis & Chemical Research: Employed in academic and industrial R&D for exploring novel synthetic pathways and creating specialized chemical libraries.

Basic Information

Product Name	1-(Bromomethyl)-2,5-Difluoro-4-Nitrobenzene
CAS No.	1260640-04-7
Molecular Formula	C7H4BrF2NO2
Molecular Weight	251.02 g/mol
Synonyms	2,5-Difluoro-4-nitrobenzyl bromide; 4-Nitro-2,5-difluorobenzyl bromide; (2,5-Difluoro-4-nitrophenyl)methyl bromide; Benzene, 1-(bromomethyl)-2,5-difluoro-4-nitro-; α-Bromo-2,5-difluoro-4-nitrotoluene; 2,5-Difluoro-α-bromo-4-nitrotoluene; 4-Nitro-2,5-difluoro-α-bromotoluene
EINECS	Contact for details

Quality Control

Our 1-(Bromomethyl)-2,5-Difluoro-4-Nitrobenzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.