Description

(2-Cyano-4-Fluorophenyl)Methanesulfonyl Chloride is a high-value sulfonyl chloride derivative, a critical building block in modern organic synthesis. Its core value lies in its dual functional groups, enabling it to act as a versatile electrophile for constructing complex sulfonamide and sulfonate ester linkages. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and advanced intermediates requiring precise fluorinated and cyano-substituted architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides with enhanced activity and selectivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the creation of specialized polymers and functional materials.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	(2-Cyano-4-Fluorophenyl)Methanesulfonyl Chloride
CAS No.	1258652-29-7
Molecular Formula	C8H5ClFNO2S
Molecular Weight	233.64 g/mol
Synonyms	2-Cyano-4-fluorobenzenemethanesulfonyl chloride; 4-Fluoro-2-cyanobenzenemethanesulfonyl chloride; (4-Fluoro-2-cyanophenyl)methanesulfonyl chloride; Methanesulfonyl chloride, (2-cyano-4-fluorophenyl)-; 1258652-29-7; (2-Cyano-4-fluorophenyl)methanesulfonyl chloride
EINECS	Contact for details

Quality Control

Our (2-Cyano-4-Fluorophenyl)Methanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.