Description

Benzonitrile, 5-Amino-2,3-Difluoro- CAS NO 1247885-41-1 is a high-value, multi-functional aromatic nitrile building block featuring both amino and fluorine substituents. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique structure enables precise molecular modifications. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the difluoro and amino groups contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers and liquid crystals, where its aromatic core and substituents influence material properties.
• Fluorinated Compound Library: A valuable scaffold for constructing diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Dye and Pigment Intermediate: Acts as an intermediate in the synthesis of specialized dyes and pigments, leveraging the amino group for chromophore development.

Basic Information

Product Name	Benzonitrile, 5-Amino-2,3-Difluoro-
CAS No.	1247885-41-1
Molecular Formula	C7H4F2N2
Molecular Weight	154.12 g/mol
Synonyms	5-Amino-2,3-difluorobenzonitrile; 2,3-Difluoro-5-aminobenzonitrile; 5-Amino-2,3-difluorobenzene carbonitrile; 3-Amino-4,5-difluorobenzonitrile; 2,3-Difluoro-5-cyanobenzeneamine; 5-Cyano-2,3-difluoroaniline; 2,3-Difluoro-5-nitrileaniline; 5-Amino-2,3-difluorophenyl cyanide
EINECS	Contact for details

Quality Control

Our Benzonitrile, 5-Amino-2,3-Difluoro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.