Description

2-(Difluoromethoxy)-4-Methyl-1-Nitrobenzene is a specialized fluorinated aromatic nitro compound, serving as a valuable building block in advanced organic synthesis. Its unique difluoromethoxy substituent adjacent to a nitro group makes it a critical intermediate for introducing specific functionalities into target molecules. This compound is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluoromethoxybenzene core structure.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the difluoromethoxy group can enhance biological activity and metabolic stability.
• Material Science: Potential monomer or modifier in the creation of specialty polymers and liquid crystals with tailored electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitutions, and reduction reactions to create more complex fluorinated compounds.
• Chemical Research & Development: Serves as a standard or reference material in analytical and process development laboratories.

Basic Information

Item	Details
Product Name	2-(Difluoromethoxy)-4-Methyl-1-Nitrobenzene
CAS No.	1245772-14-8
Molecular Formula	C8H7F2NO3
Molecular Weight	203.14 g/mol
Synonyms	1-Nitro-2-(difluoromethoxy)-4-methylbenzene; 4-Methyl-2-(difluoromethoxy)-1-nitrobenzene; 2-(Difluoromethoxy)-4-methylnitrobenzene; α,α-Difluoro-4-methyl-2-nitroanisole; 2-Nitro-5-methylphenyl difluoromethyl ether
EINECS	Contact for details

Quality Control

Every batch of 2-(Difluoromethoxy)-4-Methyl-1-Nitrobenzene is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.