Description

Glucocorticoid Receptor Agonist CAS NO 1245526-82-2 is a potent and selective synthetic small molecule designed for targeted glucocorticoid receptor (GR) modulation. This compound is crucial for advanced research in endocrinology, immunology, and metabolic disease pathways, offering a valuable tool for understanding receptor-mediated signaling. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies engaged in drug discovery and mechanistic studies.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the discovery of novel anti-inflammatory and immunosuppressive therapies.
• Mechanistic Biological Studies: Used in in vitro and in vivo models to investigate GR signaling pathways, gene expression regulation, and receptor-ligand interactions.
• High-Throughput Screening (HTS): Employed as a control compound in assays to identify and validate new GR-targeting drug candidates.
• Biochemical Assay Development: Acts as a critical reagent for developing and calibrating assays measuring GR agonist activity and binding affinity.
• Preclinical Evaluation: Utilized in animal models to study the efficacy, pharmacokinetics, and safety profiles of GR-targeted therapeutic approaches.
• Metabolic Disorder Research: Applied in studies exploring the role of glucocorticoid receptors in glucose homeostasis, lipid metabolism, and related disorders.

Basic Information

Product Name	Glucocorticoid Receptor Agonist
CAS No.	1245526-82-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GR Agonist 1245526-82-2; Selective Glucocorticoid Receptor Agonist; GR Modulator; Glucocorticoid Receptor Ligand; Synthetic GR Agonist; CAS 1245526-82-2; Non-steroidal GR Agonist; Research Compound 1245526-82-2
EINECS	Contact for details

Quality Control

Our Glucocorticoid Receptor Agonist is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability, consistency, and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect this light-sensitive material from moisture and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.