Description

Cetirizine Glycerol Ester is a key pharmaceutical intermediate, specifically a prodrug derivative of the widely used antihistamine cetirizine. This compound is designed to enhance bioavailability and patient compliance by modifying the physicochemical properties of the parent drug. It is primarily utilized by pharmaceutical manufacturers and R&D laboratories engaged in the development of advanced drug delivery systems and novel therapeutic formulations.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of advanced cetirizine-based drug formulations.
• Prodrug Development: Serves as a critical building block for creating prodrugs aimed at improving solubility, stability, or absorption profiles.
• Controlled-Release Formulations: Used in research and production of sustained or modified-release oral dosage forms.
• API Synthesis: A precursor in the manufacturing process of Active Pharmaceutical Ingredients (APIs) for allergy medications.
• Pharmaceutical R&D: Employed in academic and industrial research for studying ester-based drug modifications and metabolic pathways.
• Excipient Compatibility Studies: Used in pre-formulation studies to assess interactions with other tablet or capsule components.

Basic Information

Product Name	Cetirizine Glycerol Ester
CAS No.	1243652-36-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cetirizine Glycerol Monoester; 2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid glycerol ester; Glycerol ester of Cetirizine; Cetirizine Glycerides; Cetirizine Glyceryl Ester; Cetirizine Prodrug Ester
EINECS	Contact for details

Quality Control

Our Cetirizine Glycerol Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing specifications such as assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.