Description

Doxorubicinol Citrate (Mixture Of Diastereomers) is a key pharmaceutical intermediate and metabolite of the widely used anthracycline chemotherapeutic agent, doxorubicin. Its significance lies in its role in research related to drug metabolism, efficacy, and toxicity studies, providing critical insights for oncology drug development. This compound is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) focused on cancer therapeutics and analytical standards.

Application

• Pharmaceutical Intermediate: Critical for the synthesis and development of advanced anthracycline-based chemotherapeutic agents and their derivatives.
• Metabolite Reference Standard: Used as a certified reference material in bioanalytical laboratories for quantifying doxorubicin and its metabolites in pharmacokinetic and pharmacodynamic studies.
• Biochemical Research: Employed in in-vitro and in-vivo studies to investigate the mechanisms of action, cardiotoxicity, and metabolic pathways of anthracycline drugs.
• Quality Control & Assurance: Serves as a system suitability standard in HPLC and LC-MS methods for the analysis of doxorubicin API and finished drug products.
• Drug Discovery & Development: Utilized in preclinical research to model metabolite activity and to support the development of next-generation oncology treatments with improved safety profiles.

Basic Information

Product Name	Doxorubicinol Citrate (Mixture Of Diastereomers)
CAS No.	1242592-26-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Doxorubicinol Citrate; Doxorubicinol citrate salt; 13-Dihydrodoxorubicin citrate; (8S,10S)-8-Glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-5,12-naphthacenedione citrate; Doxorubicin metabolite citrate; Adriamycinol citrate
EINECS	Contact for details

Quality Control

Our Doxorubicinol Citrate is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or CoA. Keep the container in a dry, well-ventilated place. For long-term storage, consider storing under inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Reddish-orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥95.0%
Related Substances (HPLC)	Total impurities ≤5.0%
Water Content (KF)	≤5.0%
Residue on Ignition	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.