Description

4-Chloro-2-Fluoro-5-Methylphenylacetonitrile is a versatile and high-value halogenated aromatic nitrile building block. This compound is critical for the synthesis of advanced agrochemicals and pharmaceuticals, where its unique substitution pattern enables the creation of molecules with targeted biological activity. It is primarily sought after by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for constructing complex heterocyclic systems and active ingredients.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, particularly those targeting specific plant enzymes or pests.
• Pharmaceutical Building Block: Used in medicinal chemistry for the construction of drug candidates, especially those containing fluorinated and chlorinated aromatic rings for enhanced metabolic stability and bioavailability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Chloro-2-Fluoro-5-Methylphenylacetonitrile
CAS No.	1242314-99-3
Molecular Formula	C9H7ClFN
Molecular Weight	183.61 g/mol
Synonyms	2-(4-Chloro-2-fluoro-5-methylphenyl)acetonitrile; (4-Chloro-2-fluoro-5-methylphenyl)acetonitrile; 4-Chloro-2-fluoro-5-methylbenzyl cyanide; 2-Fluoro-4-chloro-5-methylphenylacetonitrile; 5-Methyl-4-chloro-2-fluorophenylacetonitrile; 1242314-99-3; 4-Chloro-2-fluoro-5-methylbenzenacetonitrile
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluoro-5-Methylphenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are kept tightly sealed after opening to minimize exposure to moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.