Description

4-Chloro-2-Fluoro-5-Nitro-Benzonitrile is a high-purity, multi-functional aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring chloro, fluoro, and nitro substituents on a benzonitrile core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzonitrile scaffold.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the halogen and nitro groups contribute to biological activity.
• Material Science Research: Serves as a building block for developing specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex dyes and organic pigments due to its reactive nitro and cyano groups.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create biaryl structures.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry research to explore new synthetic pathways.

Basic Information

Product Name	4-Chloro-2-Fluoro-5-Nitro-Benzonitrile
CAS No.	1242269-80-2
Molecular Formula	C7H2ClFN2O2
Molecular Weight	200.55 g/mol
Synonyms	5-Nitro-2-fluoro-4-chlorobenzonitrile; 2-Fluoro-4-chloro-5-nitrobenzonitrile; 4-Chloro-2-fluoro-5-nitrobenzonitrile; Benzonitrile, 4-chloro-2-fluoro-5-nitro-; 1242269-80-2; 2-Fluoro-4-chloro-5-nitro-benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2-Fluoro-5-Nitro-Benzonitrile is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.