Description

1-Bromo-3,4-difluoro-2-isopropoxybenzene is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is valued for its unique substitution pattern, which allows for selective further functionalization, making it a critical intermediate in the development of complex molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing difluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the bromo and fluoro substituents modulate biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for creating specialized aromatic cores used in electronic display and lighting technologies.
• Ligand & Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysis and organocatalysts.
• Polymer & Resin Modification: Incorporated into polymer backbones to impart specific properties like chemical resistance or altered refractive index.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.

Basic Information

Product Name	1-Bromo-3,4-difluoro-2-isopropoxybenzene
CAS No.	1242070-97-8
Molecular Formula	C9H9BrF2O
Molecular Weight	251.07 g/mol
Synonyms	2-Bromo-4,5-difluoro-1-isopropoxybenzene; 3,4-Difluoro-2-isopropoxy-1-bromobenzene; Benzene, 1-bromo-3,4-difluoro-2-(1-methylethoxy)-; 1-Isopropoxy-2-bromo-4,5-difluorobenzene; 4,5-Difluoro-2-isopropoxybromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3,4-difluoro-2-isopropoxybenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures consistency and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.