Description

1-tert-Butyl 3-Ethyl 5-Fluoropiperidine-1,3-Dicarboxylate is a high-purity fluorinated piperidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with tailored pharmacological properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, especially in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides with improved efficacy and selectivity.
• Chemical Research: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Fluorinated Compound Development: The fluorine atom introduces desirable metabolic stability and bioavailability, making it crucial for modern drug design.

Basic Information

Product Name	1-tert-Butyl 3-Ethyl 5-Fluoropiperidine-1,3-Dicarboxylate
CAS No.	1241725-68-7
Molecular Formula	C13H22FNO4
Molecular Weight	275.32 g/mol
Synonyms	tert-Butyl 3-ethyl 5-fluoropiperidine-1,3-dicarboxylate; 5-Fluoropiperidine-1,3-dicarboxylic acid 1-tert-butyl 3-ethyl ester; 1-Boc-3-ethyl 5-fluoropiperidine-1,3-dicarboxylate; 1-(tert-Butoxycarbonyl)-3-(ethoxycarbonyl)-5-fluoropiperidine; 5-Fluoro-1,3-piperidinedicarboxylic acid 1-(1,1-dimethylethyl) 3-ethyl ester
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 3-Ethyl 5-Fluoropiperidine-1,3-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.