Description

(2S)-2-(2,3,4-Trifluorophenyl)Pyrrolidine is a high-value chiral pyrrolidine derivative, a key building block in modern pharmaceutical synthesis. Its trifluorinated aromatic ring and defined stereochemistry make it a critical intermediate for developing potent, selective drug candidates. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug discovery.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand and Catalyst Precursor: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Chemical Biology Probe Development: Employed in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with unique electronic or surface properties.

Basic Information

Product Name	(2S)-2-(2,3,4-Trifluorophenyl)Pyrrolidine
CAS No.	1241680-74-9
Molecular Formula	C10H10F3N
Molecular Weight	201.19 g/mol
Synonyms	(S)-2-(2,3,4-Trifluorophenyl)pyrrolidine; (2S)-2-(2,3,4-Trifluorophenyl)-1-pyrrolidine; 2-(2,3,4-Trifluorophenyl)pyrrolidine, (2S)-; 1241680-74-9; Pyrrolidine, 2-(2,3,4-trifluorophenyl)-, (2S)-; (S)-2-(2,3,4-Trifluorophenyl)pyrrolidine; (S)-2-(2,3,4-Trifluorophenyl)-1-pyrrolidine
EINECS	Contact for details

Quality Control

Our (2S)-2-(2,3,4-Trifluorophenyl)Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorinating agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.