Description

3-(Pentafluorosulfur)Phenylacetonitrile is a high-value fluorinated aromatic building block characterized by its unique pentafluorosulfur (SF5) substituent. This compound matters for its role in introducing the highly electronegative and lipophilic SF5 group into molecular frameworks, a key strategy in modern agrochemical and pharmaceutical design. Industries engaged in advanced research and development, particularly in life sciences and specialty materials, require this intermediate to create novel compounds with enhanced metabolic stability, bioavailability, and physical properties. Its precise synthesis and reliable supply are critical for innovators developing next-generation active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, leveraging the SF5 group to modulate lipophilicity and metabolic stability.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides where the SF5 moiety can improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Incorporated into the design of specialty electronic materials for displays and lighting due to its influence on dielectric and photophysical properties.
• Polymer & Material Science: Acts as a monomer or functionalization agent for creating high-performance polymers with specific chemical and thermal resistance.
• Chemical Synthesis Building Block: Utilized in organic synthesis for constructing complex fluorinated aromatic structures via reactions at the nitrile group.
• Life Science Probe Development: Employed in creating molecular probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	3-(Pentafluorosulfur)Phenylacetonitrile
CAS No.	1240257-91-3
Molecular Formula	C8H4F5NS
Molecular Weight	241.18 g/mol
Synonyms	3-(SF5)Phenylacetonitrile; (3-(Pentafluoro-λ6-sulfanyl)phenyl)acetonitrile; 2-[3-(Pentafluorosulfanyl)phenyl]acetonitrile; 3-(Pentafluorosulfur)benzyl cyanide; α-Cyano-3-(pentafluorosulfanyl)toluene; 3-(SF5)C6H4CH2CN; Pentafluorosulfanylphenylacetonitrile
EINECS	Contact for details

Quality Control

Every batch of 3-(Pentafluorosulfur)Phenylacetonitrile is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for advanced chemical intermediates. Comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) documenting all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.