Description

3-Fluoro-5-(Pentafluorosulfur)Phenylacetonitrile is a high-value, multi-functional fluorinated aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring both a fluorine atom and a pentafluorosulfur (SF5) group, makes it a critical intermediate for developing novel compounds with enhanced properties. This product is primarily targeted at research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create new active ingredients with improved metabolic stability, lipophilicity, and bioavailability. Its application extends to materials science for the development of specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the discovery and development of new drug candidates, particularly in creating fluorinated analogs to modulate biological activity and ADMET properties.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the SF5 group can impart superior weatherfastness and pest selectivity.
• Materials Science Precursor: Employed in the synthesis of advanced materials, including specialty polymers, liquid crystals for displays, and organic semiconductors, due to its ability to influence electronic properties and stability.
• Chemical Research & Development: Acts as a versatile building block in academic and industrial R&D for exploring novel fluorinated compound libraries and reaction methodologies.
• Ligand and Catalyst Development: Utilized in the design of novel ligands and organocatalysts for asymmetric synthesis and other specialized catalytic processes.

Basic Information

Product Name	3-Fluoro-5-(Pentafluorosulfur)Phenylacetonitrile
CAS No.	1240257-90-2
Molecular Formula	C8H3F6NS
Molecular Weight	259.18 g/mol
Synonyms	3-Fluoro-5-(pentafluoro-λ6-sulfanyl)benzeneacetonitrile; (3-Fluoro-5-(pentafluorosulfanyl)phenyl)acetonitrile; 2-[3-Fluoro-5-(pentafluoro-λ6-sulfanyl)phenyl]acetonitrile; 3-Fluoro-5-pentafluorosulfanylphenylacetonitrile; SF5-Phenylacetonitrile derivative; Fluorinated SF5-Benzyl Nitrile
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Pentafluorosulfur)Phenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (1H, 19F, 13C), HPLC, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the nitrile functionality, ensure proper segregation from strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.