Description

2-Fluoro-4-(Trifluoromethoxy)Phenylacetonitrile, 97% is a high-purity fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of fluorine and trifluoromethoxy substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in CNS and oncology research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine motifs enhance biological activity.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and electro-optical materials.
• Cross-Coupling Reactions: The nitrile and halogen groups make it a versatile substrate for Suzuki, Sonogashira, and other palladium-catalyzed couplings.
• Chemical Research & Development: A valuable building block for exploring new chemical spaces in medicinal and materials chemistry.

Basic Information

Product Name	2-Fluoro-4-(Trifluoromethoxy)Phenylacetonitrile, 97%
CAS No.	1240257-80-0
Molecular Formula	C9H5F4NO
Molecular Weight	219.14 g/mol
Synonyms	2-Fluoro-4-(trifluoromethoxy)benzyl cyanide; [2-Fluoro-4-(trifluoromethoxy)phenyl]acetonitrile; 4-(Trifluoromethoxy)-2-fluorobenzyl cyanide; 2-Fluoro-α-(trifluoromethoxy)phenylacetonitrile; (2-Fluoro-4-trifluoromethoxyphenyl)acetonitrile; α-Cyano-2-fluoro-4-(trifluoromethoxy)toluene; F-TFMOPA; FTMPAN
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(Trifluoromethoxy)Phenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure the specified 97% minimum purity and identity are met. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.