Description

3-Chloro-5-(Pentafluorosulfur)Phenylacetonitrile is a high-value, fluorinated aromatic nitrile building block of significant interest in advanced chemical synthesis. Its unique structure, featuring both chloro and pentafluorosulfur substituents, makes it a critical intermediate for developing novel compounds with tailored properties. This product is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by material scientists exploring advanced functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing the pentafluorosulfur (SF5) pharmacophore, known to enhance metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the SF5 group can improve biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display technologies and organic light-emitting diodes (OLEDs), contributing to improved performance and stability.
• Polymer & Resin Modification: Employed to incorporate fluorine into polymer backbones, enhancing material properties such as chemical resistance, thermal stability, and low surface energy.
• Specialty Chemical Building Block: Utilized in organic synthesis for constructing complex fluorinated molecules for various high-value applications in catalysis and surface science.

Basic Information

Product Name	3-Chloro-5-(Pentafluorosulfur)Phenylacetonitrile
CAS No.	1240257-75-3
Molecular Formula	C8H3ClF5NS
Molecular Weight	275.63 g/mol
Synonyms	2-(3-Chloro-5-(pentafluoro-λ6-sulfanyl)phenyl)acetonitrile; (3-Chloro-5-pentafluorosulfanylphenyl)acetonitrile; 3-Chloro-5-(SF5)phenylacetonitrile; 3-Chloro-5-(pentafluorosulfur)benzyl cyanide; α-(3-Chloro-5-pentafluorosulfanylphenyl)acetonitrile; Phenylacetonitrile, 3-chloro-5-(pentafluorosulfur)-; CAS 1240257-75-3
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-(Pentafluorosulfur)Phenylacetonitrile is produced and analyzed under strict quality management protocols to ensure consistency and high purity for research and scale-up applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and structural confirmation, to meet the exacting standards required for advanced synthetic chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.