Description

2-Fluoro-4-(Pentafluorosulfur)Benzonitrile is a high-value, fluorinated aromatic building block characterized by its unique combination of a nitrile group and a pentafluorosulfanyl (SF5) substituent. This compound matters for its role in advanced material science and pharmaceutical research, where the SF5 group is prized as a "super-trifluoromethyl" group for imparting exceptional metabolic stability, lipophilicity, and electronic properties. Industrial researchers and process chemists in agrochemical, pharmaceutical, and specialty polymer sectors need this intermediate to develop novel active ingredients and high-performance materials with enhanced properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the discovery and development of new drug candidates, particularly for incorporating the metabolically robust pentafluorosulfanyl moiety.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides where the SF5 group can improve biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs) due to its strong electron-withdrawing character.
• Specialty Polymer Modification: Employed to introduce fluorine into polymer backbones or side chains, enhancing chemical resistance, thermal stability, and lowering dielectric constants.
• Ligand & Catalyst Development: Useful in creating novel fluorinated ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorinated Surfactant & Surface Modifier: A precursor for compounds that lower surface tension in demanding industrial applications.

Basic Information

Product Name	2-Fluoro-4-(Pentafluorosulfur)Benzonitrile
CAS No.	1240256-91-0
Molecular Formula	C7HF6NS
Molecular Weight	245.15 g/mol
Synonyms	4-Cyano-3-fluorophenylsulfur pentafluoride; 2-Fluoro-4-(pentafluoro-λ6-sulfanyl)benzonitrile; 2-Fluoro-4-(SF5)benzonitrile; Benzonitrile, 2-fluoro-4-(pentafluorosulfur)-; 4-SF5-2-Fluorobenzonitrile; 2-Fluoro-4-pentafluorosulfanylbenzonitrile; 2-Fluoro-4-(sulfur pentafluoride)benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(Pentafluorosulfur)Benzonitrile is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects with custom purity grades and scalable synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry and inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.