Description

2-Fluoro-4-(Pentafluorosulfur)Phenylacetonitrile is a high-value, fluorinated aromatic nitrile building block of significant interest in advanced chemical synthesis. Its unique structure, featuring both fluorine and a pentafluorosulfur (SF5) group, makes it a critical intermediate for developing novel compounds with tailored properties. This specialty chemical is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by material scientists exploring advanced functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases, where the SF5 group can enhance metabolic stability and lipophilicity.
• Agrochemical Active Ingredient Development: Used in research to create new herbicides, fungicides, and insecticides, leveraging the unique electronic and steric properties of the pentafluorosulfur moiety for improved efficacy and environmental profile.
• Liquid Crystal & OLED Material Research: Acts as a building block for fluorinated components in electronic display materials, where its structure can influence dielectric anisotropy and thermal stability.
• Advanced Polymer & Resin Modification: Incorporated into specialty polymers to impart specific characteristics such as chemical resistance, low surface energy, or altered refractive index.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D as a versatile substrate for developing new fluorination methodologies and cross-coupling reactions.

Basic Information

Product Name	2-Fluoro-4-(Pentafluorosulfur)Phenylacetonitrile
CAS No.	1240256-87-4
Molecular Formula	C8H3F6NS
Molecular Weight	259.17 g/mol
Synonyms	2-Fluoro-4-(pentafluoro-λ⁶-sulfanyl)benzeneacetonitrile; 4-(SF5)-2-Fluorophenylacetonitrile; (2-Fluoro-4-pentafluorosulfanylphenyl)acetonitrile; 2-Fluoro-4-(SF5)phenylacetonitrile; α-Cyano-2-fluoro-4-pentafluorosulfanyltoluene; Benzeneacetonitrile, 2-fluoro-4-(pentafluoro-λ⁶-sulfanyl)-; 2-Fluoro-4-pentafluorosulfurylbenzyl cyanide
EINECS	Contact for details

Quality Control

Our production of 2-Fluoro-4-(Pentafluorosulfur)Phenylacetonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Every lot is characterized using advanced analytical techniques including NMR (¹H, ¹⁹F, ¹³C), HPLC, GC-MS, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.