Description

2-Fluoro-4-(Trifluoromethoxy)Benzonitrile, 97% is a high-purity fluorinated aromatic nitrile building block, essential for advanced organic synthesis. This compound is valued for its unique trifluoromethoxy and fluorine substituents, which are critical for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Functional Material Development: Employed in creating specialty polymers, coatings, and advanced materials that require specific fluorine-induced properties like chemical resistance and low surface energy.
• Chemical Research & Development: A versatile building block for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution in academic and industrial R&D settings.

Basic Information

Product Name	2-Fluoro-4-(Trifluoromethoxy)Benzonitrile, 97%
CAS No.	1240256-78-3
Molecular Formula	C8H3F4NO
Molecular Weight	205.11 g/mol
Synonyms	2-Fluoro-4-(trifluoromethoxy)benzonitrile; 4-Cyano-3-fluoro-1-(trifluoromethoxy)benzene; 2-Fluoro-α,α,α-trifluoro-p-toluonitrile; 2-Fluoro-4-trifluoromethoxybenzonitrile; 4-(Trifluoromethoxy)-2-fluorobenzonitrile; Benzonitrile, 2-fluoro-4-(trifluoromethoxy)-; 2-Fluoro-4-trifluoromethoxy phenyl cyanide
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(Trifluoromethoxy)Benzonitrile, 97% is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency meet the specified standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.