Description

4-Iodo-3,5-Bis-(Trifluoromethyl)-1H-Pyrazole, 97% is a high-purity, halogenated pyrazole derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring iodine and trifluoromethyl groups, makes it a versatile intermediate for introducing specific functionalities into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting neurological disorders and metabolic diseases.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its halogen and fluorine content.
• Cross-Coupling Reactions: Serves as a valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) for constructing complex biaryl and conjugated systems.
• Fluorine Chemistry: Important reagent for introducing trifluoromethyl groups into heterocyclic scaffolds, modulating the lipophilicity and metabolic stability of compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions.

Basic Information

Product Name	4-Iodo-3,5-Bis-(Trifluoromethyl)-1H-Pyrazole, 97%
CAS No.	1239511-06-8
Molecular Formula	C5HF6IN2
Molecular Weight	335.97 g/mol
Synonyms	4-Iodo-3,5-bis(trifluoromethyl)-1H-pyrazole; 1H-Pyrazole, 4-iodo-3,5-bis(trifluoromethyl)-; 3,5-Bis(trifluoromethyl)-4-iodo-1H-pyrazole; 4-Iodo-3,5-di(trifluoromethyl)pyrazole; 4-Iodo-3,5-bis(trifluoromethyl)pyrazole; CAS 1239511-06-8
EINECS	Contact for details

Quality Control

Our 4-Iodo-3,5-Bis-(Trifluoromethyl)-1H-Pyrazole, 97% is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the specified standards. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.