Description

2-(2-Fluoro-5-Methylphenyl)Benzonitrile is a specialized aromatic nitrile derivative featuring a fluoro-methylphenyl substituent, making it a valuable building block in advanced organic synthesis. This compound is critical for research and development in the pharmaceutical and agrochemical sectors, where its unique structure enables the creation of novel active ingredients. It is primarily sought after by R&D chemists and process development scientists working on new drug candidates, crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for targets requiring fluorinated biphenyl-like scaffolds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand & Catalyst Development: Acts as a starting material for constructing sophisticated ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science: Employed in the research of organic electronic materials, such as OLEDs or semiconductors, where its aromatic and nitrile groups contribute to electron transport properties.
• Chemical Biology Probes: Utilized as a core structure for developing fluorescent tags or molecular probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	2-(2-Fluoro-5-Methylphenyl)Benzonitrile
CAS No.	1238333-79-3
Molecular Formula	C14H10FN
Molecular Weight	211.24 g/mol
Synonyms	2-(2-Fluoro-5-methylphenyl)benzonitrile; [1,1'-Biphenyl]-2-carbonitrile, 2'-fluoro-5'-methyl-; 2'-Fluoro-5'-methyl-[1,1'-biphenyl]-2-carbonitrile; 2-(2-Fluoro-5-methylphenyl)phenyl cyanide; 2-Cyano-2'-fluoro-5'-methylbiphenyl; 2-Fluoro-5-methyl-2'-cyanobiphenyl; Benzonitrile, 2-(2-fluoro-5-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 2-(2-Fluoro-5-Methylphenyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP and ISO guidelines ensures reliable material for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.