Description

Php 501 Trifluoroacetate is a high-purity trifluoroacetate salt, a key intermediate in advanced pharmaceutical synthesis and fine chemical manufacturing. This compound is valued for its role in introducing the trifluoroacetyl group, which can significantly alter the metabolic stability and bioavailability of target molecules. It is essential for research and production in pharmaceutical development, particularly for creating novel active pharmaceutical ingredients (APIs) and for use in agrochemical and material science applications.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting improved pharmacokinetic properties.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the trifluoromethyl group enhances biological activity.
• Peptide Chemistry: Employed as a protecting group reagent or a counterion in the synthesis and purification of peptide-based compounds.
• Material Science Research: Serves as a precursor or modifying agent in the development of specialty polymers and advanced organic materials.
• Analytical Chemistry: Can be used as a reference standard or reagent in chromatographic and spectroscopic analysis methods.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological mechanisms.

Basic Information

Product Name	Php 501 Trifluoroacetate
CAS No.	1236105-75-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PH-501 Trifluoroacetate; PHP 501 TFA Salt; 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 2-(1H-indazol-5-yl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5(8H)-yl)-, 2,2,2-trifluoroacetate (1:1); CS-1776; CS1776; (S)-2-(2-(1H-Indazol-5-yl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5(8H)-yl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid trifluoroacetate salt; TAS-116 Trifluoroacetate; TAS116 TFA Salt
EINECS	Contact for details

Quality Control

Our Php 501 Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.