Description

1-Fluoro-3-Isobutoxy-2-Nitrobenzene is a specialized fluorinated aromatic nitro compound with the CAS number 1233955-76-4. This high-purity intermediate is critical for advanced organic synthesis, particularly in the development of complex molecules where its unique substitution pattern enables precise structural modifications. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic scaffolds for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the fluorine atom and nitro group contribute to biological activity.
• Material Science: Serves as a precursor for advanced polymers, liquid crystals, and organic electronic materials due to its aromatic and electron-withdrawing properties.
• Dye & Pigment Synthesis: Employed in the creation of specialized colorants and photographic chemicals.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and nucleophilic aromatic substitution reactions.

Basic Information

Product Name	1-Fluoro-3-Isobutoxy-2-Nitrobenzene
CAS No.	1233955-76-4
Molecular Formula	C10H12FNO3
Molecular Weight	213.21 g/mol
Synonyms	2-Nitro-1-fluoro-3-isobutoxybenzene; 3-Isobutoxy-2-nitrofluorobenzene; 1-Fluoro-3-(2-methylpropoxy)-2-nitrobenzene; Benzene, 1-fluoro-3-(2-methylpropoxy)-2-nitro-; 1233955-76-4; FC-ISO-NBZ (common abbreviation)
EINECS	Contact for details

Quality Control

Our 1-Fluoro-3-Isobutoxy-2-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.