Description

1-Fluoro-2-Isobutoxy-3-Nitrobenzene is a high-purity, synthetically valuable fluorinated aromatic building block. This compound is essential for advanced organic synthesis, particularly in the development of complex molecules for pharmaceutical and agrochemical research. It serves as a critical intermediate for medicinal chemists and process R&D teams working on novel active ingredients, where its unique substitution pattern enables precise structural modifications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom and nitro group for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic materials.
• Chemical Synthesis: Versatile intermediate for further functionalization via reactions targeting the nitro group or the aromatic ring, enabling library synthesis for screening.
• Ligand and Catalyst Development: Useful scaffold for constructing complex ligands used in catalytic systems and coordination chemistry.

Basic Information

Product Name	1-Fluoro-2-Isobutoxy-3-Nitrobenzene
CAS No.	1233955-17-3
Molecular Formula	C10H12FNO3
Molecular Weight	213.21 g/mol
Synonyms	2-Fluoro-1-isobutoxy-3-nitrobenzene; 3-Nitro-2-fluoroanisole, isobutyl ether; Benzene, 1-fluoro-2-isobutoxy-3-nitro-; 2-Fluoro-3-nitroanisole isobutyl ether; 1-Fluoro-2-(2-methylpropoxy)-3-nitrobenzene; Isobutyl 2-fluoro-3-nitrophenyl ether; 2-Fluoro-3-nitrophenyl isobutyl ether
EINECS	Contact for details

Quality Control

Our 1-Fluoro-2-Isobutoxy-3-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.