Description

1-(3-Fluoro-2-Nitrophenyl)Pyrrolidine is a specialized fluorinated pyrrolidine derivative, serving as a crucial building block in advanced organic synthesis. Its unique structure, featuring both a nitro and a fluoro substituent on the aromatic ring, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and enzyme inhibitors.
• Agrochemical Research: Used to develop new herbicides, fungicides, and pesticides by incorporating its fluorinated aromatic moiety into lead structures.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Acts as a versatile reagent for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution (SNAr) due to its reactive nitro and fluoro groups.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Academic & Contract Research: Essential for fundamental research in heterocyclic and fluorine chemistry at universities and CROs (Contract Research Organizations).

Basic Information

Product Name	1-(3-Fluoro-2-Nitrophenyl)Pyrrolidine
CAS No.	1233951-55-7
Molecular Formula	C10H11FN2O2
Molecular Weight	210.21 g/mol
Synonyms	1-(3-Fluoro-2-nitrophenyl)pyrrolidine; N-(3-Fluoro-2-nitrophenyl)pyrrolidine; Pyrrolidine, 1-(3-fluoro-2-nitrophenyl)-; 3-Fluoro-2-nitro-N-pyrrolidinoaniline; 2-Nitro-3-fluoro-N-pyrrolidinoaniline; 1-(3-Fluoro-2-nitro-phenyl)-pyrrolidine; 3-Fluoro-2-nitrophenylpyrrolidine
EINECS	Contact for details

Quality Control

Our 1-(3-Fluoro-2-Nitrophenyl)Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.