Description

3-Iodo-4-(Trifluoromethyl)Nitrobenzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. Its unique structure, featuring iodine, trifluoromethyl, and nitro substituents, makes it a critical intermediate for creating complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated or fluorinated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create specialized ligands for catalysis, leveraging the iodine atom for further functionalization.
• Material Science Research: Acts as a monomer or building block for advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactive iodine substituent.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating compound libraries in medicinal chemistry.

Basic Information

Item	Detail
Product Name	3-Iodo-4-(Trifluoromethyl)Nitrobenzene
CAS No.	1228898-12-1
Molecular Formula	C7H3F3INO2
Molecular Weight	316.99 g/mol
Synonyms	1-Iodo-2-nitro-5-(trifluoromethyl)benzene; 2-Nitro-5-(trifluoromethyl)iodobenzene; 3-Iodo-4-(trifluoromethyl)-1-nitrobenzene; 4-(Trifluoromethyl)-3-iodonitrobenzene; 5-(Trifluoromethyl)-2-iodonitrobenzene; 2-Iodo-5-nitrobenzotrifluoride; Iodo(trifluoromethyl)nitrobenzene
EINECS	Contact for details

Quality Control

Our 3-Iodo-4-(Trifluoromethyl)Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and commercial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.