Description

4-Bromo-2-Fluoro-6-Hydroxybenzonitrile is a high-purity, multi-functional halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable scaffold for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and plant growth regulators, leveraging the fluorine and bromine atoms for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Building block for synthesizing advanced organic electronic materials, such as organic semiconductors and liquid crystals.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated aromatic nitriles.

Basic Information

Product Name	4-Bromo-2-Fluoro-6-Hydroxybenzonitrile
CAS No.	1227918-06-0
Molecular Formula	C7H3BrFNO
Molecular Weight	216.01 g/mol
Synonyms	2-Fluoro-6-hydroxy-4-bromobenzonitrile; 4-Bromo-2-fluoro-6-hydroxybenzonitrile; 6-Bromo-2-fluoro-4-cyanophenol; Benzonitrile, 4-bromo-2-fluoro-6-hydroxy-; 1227918-06-0; 4-Bromo-2-fluoro-6-hydroxy-benzonitrile
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-6-Hydroxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements of research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.