Description

3-Nitro-4-Trifluoromethylbenzonitrile is a high-value, multi-functional aromatic intermediate featuring both nitro and trifluoromethyl substituents. This compound is critical for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique electronic and steric properties enable precise molecular design. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Serves as a precursor for electron-deficient components in electronic display and lighting materials.
• Polymer Modification: Incorporated into specialty polymers to impart specific chemical resistance or thermal stability.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a precursor for other functionalized benzonitrile derivatives.
• Dye & Pigment Intermediate: Used in the production of specialized colorants for high-performance applications.

Basic Information

Product Name	3-Nitro-4-Trifluoromethylbenzonitrile
CAS No.	1227489-72-6
Molecular Formula	C8H3F3N2O2
Molecular Weight	216.12 g/mol
Synonyms	4-(Trifluoromethyl)-3-nitrobenzonitrile; 3-Nitro-4-(trifluoromethyl)benzonitrile; Benzonitrile, 3-nitro-4-(trifluoromethyl)-; 1227489-72-6; 4-Cyano-2-nitrobenzotrifluoride; 2-Nitro-α,α,α-trifluoro-p-tolunitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Nitro-4-Trifluoromethylbenzonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.