Description

Benzene, 1-Chloro-3-Fluoro-2-Nitro-5-(Trifluoromethyl)- is a high-value, multi-functional aromatic building block distinguished by its unique combination of halogen and nitro substituents. This compound is engineered to serve as a critical intermediate in advanced synthetic pathways, offering precise reactivity for constructing complex molecular architectures. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated and nitro-substituted benzene cores.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides where the trifluoromethyl and nitro groups enhance biological activity and stability.
• Material Science Research: Used in the creation of advanced polymers, liquid crystals, and electronic materials due to its electron-withdrawing substituents.
• Organic Synthesis & Catalysis: Serves as a versatile substrate in cross-coupling reactions, nucleophilic aromatic substitutions, and as a ligand precursor in catalytic systems.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where its substitution pattern influences color and fastness properties.

Basic Information

Product Name	Benzene, 1-Chloro-3-Fluoro-2-Nitro-5-(Trifluoromethyl)-
CAS No.	1226805-38-4
Molecular Formula	C7H2ClF4NO2
Molecular Weight	259.54 g/mol
Synonyms	1-Chloro-3-fluoro-2-nitro-5-(trifluoromethyl)benzene; 2-Nitro-5-(trifluoromethyl)-1-chloro-3-fluorobenzene; 3-Fluoro-2-nitro-5-(trifluoromethyl)chlorobenzene; 5-(Trifluoromethyl)-1-chloro-3-fluoro-2-nitrobenzene; Benzene, 1-chloro-3-fluoro-2-nitro-5-(trifluoromethyl)-; 1226805-38-4
EINECS	Contact for details

Quality Control

Our production of Benzene, 1-Chloro-3-Fluoro-2-Nitro-5-(Trifluoromethyl)- adheres to a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or in secondary light-proof packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.