Description

Methyl 5,5,5-Trifluoro-4-(4-Fluorophenylamino)Pent-3-Enoate is a high-value fluorinated building block and intermediate in advanced organic synthesis. This compound matters for its unique molecular architecture, incorporating both trifluoromethyl and fluorophenylamino groups, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by R&D and process chemistry teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in areas targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Material Science Precursor: Serves as a specialty monomer or additive in the research of fluorinated polymers with unique surface properties and chemical resistance.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a labeled compound in biochemical assays.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Item	Details
Product Name	Methyl 5,5,5-Trifluoro-4-(4-Fluorophenylamino)Pent-3-Enoate
CAS No.	1224599-54-5
Molecular Formula	C13H13F4NO2
Molecular Weight	291.24 g/mol
Synonyms	Methyl (2E)-5,5,5-trifluoro-4-[(4-fluorophenyl)amino]pent-2-enoate; (E)-Methyl 5,5,5-trifluoro-4-((4-fluorophenyl)amino)pent-2-enoate; 1224599-54-5; Methyl 5,5,5-trifluoro-4-(4-fluoroanilino)pent-2-enoate; 4-(4-Fluorophenylamino)-5,5,5-trifluoropent-3-enoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5,5,5-Trifluoro-4-(4-Fluorophenylamino)Pent-3-Enoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.