Description

Methyl 3-(5-Fluoro-2-(Trifluoromethyl)-1H-Indol-3-Yl)Propanoate is a high-value fluorinated indole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both fluorine and trifluoromethyl groups, is engineered to impart enhanced metabolic stability, lipophilicity, and binding affinity in target molecules. This compound is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorinated indole core contributes to biological activity.
• Material Science Research: Serves as a precursor for specialty polymers and organic electronic materials that require fluorinated aromatic components.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag due to its distinct spectroscopic signature from fluorine atoms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up services for clients in the life sciences sector.
• Academic & Institutional Research: Used in university and institutional labs for methodological studies in fluorination chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	Methyl 3-(5-Fluoro-2-(Trifluoromethyl)-1H-Indol-3-Yl)Propanoate
CAS No.	1223418-35-6
Molecular Formula	C₁₃H₁₁F₄NO₂
Molecular Weight	289.23 g/mol
Synonyms	Methyl 3-(5-Fluoro-2-(trifluoromethyl)-1H-indol-3-yl)propanoate; 3-(5-Fluoro-2-(trifluoromethyl)-1H-indol-3-yl)propanoic Acid Methyl Ester; 5-Fluoro-2-(trifluoromethyl)indole-3-propionic Acid Methyl Ester; Methyl 5-Fluoro-2-(trifluoromethyl)indole-3-propionate; 1223418-35-6; MFCD30153123
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-(5-Fluoro-2-(Trifluoromethyl)-1H-Indol-3-Yl)Propanoate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be stored away from light. Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Incompatible with strong alkalis and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.